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Health Benefits of Butyric Acid

Author: Doreen Gao

Sep. 05, 2022

51 0 0

Tags: Chemicals

Fluorine Compound

1. Weight loss


Butyric acid is popular for its potential ability to help people shed excess weight. Scientific evidence suggests that obese people (and those with type II diabetes) have a different composition of gut bacteria. Short-chain fatty acids are thought to play a positive role, along with probiotics, in preventing metabolic syndrome, which almost always includes abdominal obesity.


Short-chain fatty acids such as butyric acid help regulate the balance between fatty acid synthesis and lipolysis. In a 2007 animal study, after five weeks of BTA treatment, obese mice lost 10.2% of their body weight and 10% of their body fat. Butyric acid has also been shown to improve insulin sensitivity, which helps prevent weight gain.


To date, most of the evidence linking BTA supplementation to weight loss has been based on animal studies, but it does show positive effects in the natural treatment of obesity.



2. Potential colorectal cancer treatment


Several studies have shown the potential ability of butyric acid to fight cancer, especially colon cancer. It has actually shown the ability to "modify nuclear structure" and induce death in colon cancer cells. This may be an important reason why increased fiber intake is associated with a decrease in colon cancer, as higher fiber intake usually equates to a greater presence of butyric acid in the colon.


According to a 2011 study published in the International Journal of Cancer, "The role of short-chain fatty acids, particularly butyrate, in colon cancer treatment has been extensively studied, and their tumor suppressive function is believed to be due to their intracellular effects." This laboratory study further showed that butyrate treatment led to an increase in programmed cell death in colon cancer cells.


According to a 2014 scientific article, it appears that "a high-fiber diet prevents colorectal tumors in a microbiota- and butyrate-dependent manner." What does this mean? It means that it is likely that getting a lot of fiber by itself does not protect against cancer. It is eating a diet rich in healthy fiber, with good enough gut flora and enough BTA present in the body to provide cancer defense in the colon.




3. Irritable bowel syndrome (IBS) relief



Butyric acid in general can have a very positive impact on intestinal health, which can greatly affect the health of your entire body. Short-chain fatty acids such as butyric acid can help keep your intestines healthy and sealed, thus preventing leaky gut syndrome and the various problems associated with leaky gut, such as IBS symptoms. This is a digestive disorder characterized by a group of common symptoms, including bowel changes and abdominal pain.


A scientific article published in Gastroenterology Reviews explores the potential of butyric acid as a dietary therapy for IBS, based on the extensive research conducted to date. The researchers conclude that "butyrate supplementation appears to be a promising therapy for the treatment of IBS."




Some of the notable 2012 studies included in the article were a double-blind, randomized, placebo-controlled study involving 66 adult patients with IBS who received either a 300 mg daily dose of microencapsulated butyric acid or a placebo in addition to standard treatment.


After four weeks, researchers found that subjects taking butyric acid had significantly less frequent abdominal pain during bowel movements. after 12 weeks, subjects in the BTA group had less frequent spontaneous abdominal pain, postprandial abdominal pain, abdominal pain during defecation, and post-defecation urge.




4. Treatment of Crohn's disease



Crohn's disease is an inflammatory bowel disease (IBD) characterized by inflammation of the lining of the gastrointestinal tract, abdominal pain, severe diarrhea, fatigue, weight loss, and malnutrition. A small study published in 2005 in the journal Alimentary Pharmacology & Therapeutics found that "oral butyrate is safe and well tolerated and may be effective in inducing clinical improvement/remission of Crohn's disease. "


Another study in 2013 showed that butyric acid may reduce pain during bowel movements and intestinal inflammation, both of which are very helpful in Crohn's disease and other inflammatory bowel diseases.


Short-chain fatty acids like BTA do play a crucial role in maintaining the integrity of the intestinal barrier, which can help prevent leaky gut and avoid IBDs like Crohn's disease.




We yu feng group provide Butyric Acid packed in 200litre drums or IBC. The net weight is 180KG/drum or 900kg/IBC. If you are interested in our products, please contact us now!